Therapist Susan Fee signs up herself and her daughter for a stress management research study, and while suffering from a panic attack, comedian Kenice Mobley reflects on a psychology experiment about the impact of race on comfort that she took part in.

Shawn Musgrave's seizures make him feel like he's experiencing deja vu, and Shane Mauss’ bipolar disorder causes him to lose his sense of reality.

Witnessing mistakes health care professionals made after her dad has a stroke, Jenn Kamara vows never to work in medicine, and for Theresa Ball, it seems like everything in life is keeping her from her dream of becoming a nurse.

Comedian Amy Veltman doesn’t want to acknowledge her embarrassing gastrointestinal issues, and Mike Lambert seeks a friend’s help to pick out new glasses, but his secret body dysmorphia threatens to undo him.

Scientist Gretchen Goldman struggles to protect the data and integrity of science under the new Trump administration, and journalist Liz Landau feels the wrath of the internet when she covers a study about women and their voting preferences.

After surviving breast cancer, comedian Ophira Eisenberg hates the pink breast cancer awareness ribbon, and after the sudden death of his mom, Richard Kemeny feels numb to the world and his feelings.

Devon Kodzis thought they had their anxiety under control until a routine doctor appointment, and naturally anxious neuroscientist Tammy Spence becomes preoccupied with her dog’s health.

One moment Keith Mellnick is cycling home, the next he’s in the emergency room of the hospital with no idea what happened to him, and medical student Fabiola Plaza feels compelled to help a woman on the New York subway get a doctor’s appointment.

After a neurological disorder leaves Tracey Starin visually impaired, she struggles to fill the void of her love for reading, and at first comedian Ayanna Dookie doesn’t take her Lupus diagnosis seriously.

When Barbara Todd isn’t with her dad when he passes, she searches for forgiveness, and grad student Nina Christie’s preconceived notions of the Skid Row needle exchange get turned on their head when she begins volunteering there.