Jamie Brickhouse's HIV-positive status becomes a point of tension at the dentist's office, and diagnosed with autism spectrum disorder as a child, Anders Lee struggles with this identity as an adult preparing to donate sperm.

After her mom's version of the sex talk confuses her, Khadija Aweis is determined to make sure her little brother has clarity, and when Leesha Maliakal takes on an ambitious research project designing an app for marathon spectators, her supportive dad tries to help.

When his mother his diagnosed with breast cancer, Ian Anthony has to take care of her, even though she didn't always do the best job of taking care of him, determined to make it on her own, Yaihara Fortis Santiago leaves her home in Puerto Rico for grad school, but her father still wants to protect her.

Shawn Hercules is a successful gospel radio deejay in Barbados, but he dreams of a different kind of life in science, and Emma Young feels ready for her first real job in science, surveying northern spotted owls, until she encounters some unexpected fears.

As a science teacher Mamoudou N'Diaye was supposed to have all the answers, but he struggles to explain being Black in the USA, and Rhonda Key fights to be taken seriously by her white co-workers and students when she gets a job at a middle school.

To cheer up her ailing father, Victoria Ruiz decides to smuggle a turtle into his hospital room, and Stacey Bader Curry finally meets a nice guy -- the only catch is, he needs a liver.

Massih Moayedi survives cancer, but the recovery throws his life off track, and after his 20-year-old daughter dies suddenly, Paul Battista has to relearn what his role in life is.

As a medical student Roger Mitchell Jr. sees a patient that makes him reflect on violence and police in the Black community.

Padraic Stanley gets a fresh start when his abusive father gets diagnosed with Alzheimer's dementia, and after meeting a man with a rare memory disorder, Paul Aflalo reconsiders his own memories.

Digital consultant Phong Tran navigates his relationship through various digital platforms, and fed up with feeling lonely, Sufian Zhemukhov embarks on a data driven analysis of his own unlikability.