After finally getting together in their forties, Chris Wade and his wife are determined to have a baby -- even if it means following some unconventional advice, and struggling to conceive, Sara Sweet makes her third attempt at intrauterine insemination just before her family's Christmas gathering.

A routine procedure with one of the primates in her lab becomes much more complicated when neuroscientist Paula Croxson cuts herself with the scalpel, and when surgeon Bhuvanesh Singh sees his patient back in the hospital months after what he thought was a successful surgery, he grapples with feelings of failure.

Luke Rosen signs his daughter up for a research study to find out what's causing her seizures and ends up having to fight to find the answers, and after doctors are unable to prevent her daughter's daily seizures, Tracy Dixon-Salazar decides to take matters into her own hands.

After Kenny Kinds begins lying to his parents about his grades, he has to question why he is in engineering school in the first place, and after a tragedy, Brianna Shaughnessy discovers a different way to heal at the Great Barrier Reef.

As the scientist in the family, Steve Scott takes on a new role when his dad must undergo heart surgery, and Tajana Schneiderman struggles to live up to the expectations and sacrifices of her brilliant scientist mother.

When pharmacy professor Lindsay Acree volunteers at a local needle exchange, her beliefs about addiction are challenged, and engineering PhD student Jeannie Purchase sets out to help a couple in rural South Carolina who have endured dirty tap water for a decade.

Veterinarian Rodrigo Solis thinks he's found the perfect job -- taking care of horses in the Mexican Army -- until a new commander takes over, and weeks before an important performance, opera singer Laura Crocco notices there's something wrong with her voice.

Lonely after her move to New York City, Adrien Behn finds a friend in her copper IUD, and while recovering from prostate cancer surgery, Dana Strout finds a creative solution to his incontinence.

When biologist Andrew Holding's new baby stops feeding, his scientific instincts are put to the test, and after finding out her mother has breast cancer, high school teacher Nakeysha Roberts Washington gets hit with the news that one of her students has a brain tumor.

After turning down a tenure position, Sarah Brady struggles to adapt to her new life as the spouse of a physician, and as he grows up, Ed Greco's two great loves -- his high school sweetheart, and physics -- come into conflict.