During her pediatric residency, Erica Martinez finds herself struggling to feel empathy for some of her patients, and while working as a doctor in South Bronx, Karinn Glover feels overwhelmed and powerless when trying to help a patient with substance use issues.

When Neeti Jain dissects her first fish in the lab, she feels like she’s not cut out to be a scientist in marine ecology, and as the new chief public health officer, Harold Cox feels out of his depth when their office receives a package with what appears to be anthrax.

When Luis Melo doesn’t see his name on a report that he spent nine months working on, he decides to confront his boss, and when another professor at a conference makes an inappropriate comment toward Sara Maloni, she decides to speak up.