Raised as a creationist, Jennifer Colbourne falls in love with evolutionary science, and Herman B. White leaves his hometown of Tuskegee behind to pursue physics -- but his Alabama roots help him make a surprising connection.

As a first-year teacher, Matt Baker feels overwhelmed -- especially when his principal is less than supportive, and a graduate student is sexually assaulted by a labmate.

Author Kate Greathead sets off on a cross-country drive to escape her anxiety, and after years of studying worms, Tracy Chong begins to wonder if they might hold the key to alleviating hunger. 

When Sandi Marx develops cognitive symptoms of lupus, she worries she'll lose the aspects of her personality that she values most, and chemist Toria Stafford's untreated mental illness starts to overwhelm both her science and her personal life. 

Feeling isolated in her new job as a particle accelerator operator, Cindy Joe finds comfort in her unconventional pet, and Patrick Honner starts to doubt his lifelong love of math when grad school becomes a lonely experience.

Writer Matthew Dicks is startled to learn that his dog is in surgery -- and that he agreed to it the night before, and climatologist Simon Donner misses the ride to his field site in Madagascar, and must find his way there on his own. 

Science communicator Anthony Morgan receives an invitation to be vacuum-sealed to the bottom of a helicopter -- for science, and as a medical student, Elorm Avakame befriends a patient who is dying from alcoholism.

Comedian Josh Gondelman is threatened with a lawsuit after he reviews a new sexual enhancement product, and neuroscientist Heather Berlin and rapper Baba Brinkman try to use science to figure out if they belong together.

On her first day working in the Obama White House, microbiologist Jo Handelsman receives some bad news, and after a confrontation with a student, math teacher Sage Forbes-Gray begins to question whether she's the ally she thought she was.

Science educator Charlie Cook experiments with coming out to students, and marine biologist Shayle Matsuda adapts to his new identity as a transgender man while on assignment in the Philippines.