Zoe Wisnoski takes matters into her own hands when her son has months of ongoing fevers, and during the pandemic, epidemiologist Bryon Backenson becomes disheartened when the public stops cooperating with public health authorities.

When Yves Jeffcoat is diagnosed with multiple sclerosis, she isn’t sure how to manage this new normal, and Jameer Pond keeps ending up in relationships he doesn’t want to be in, so his therapist suggests he take a sex sabbatical.

Kate Marvel's dream of being a genius takes her to Cambridge to study astrophysics, and when Joe Normandin begins to question his sexuality as a teenager, he turns to neuroscience for help.

After debunking Bella Hadid’s treatment for chronic lyme disease, Fola Olusanya finds herself in a heated debate with another TikToker, and during the pandemic, infectious disease researcher and science communicator Laurel Bristow receives a flood of hate mail.

After giving birth to her second child, Julie Raskin doesn’t know how to handle his constant crying and need to nurse, and as a new immigrant and surprise cancer patient, Emmanuel Paul navigates the complexities of the US healthcare system.

Eva Chebishev gets voted “Most Organized” in first grade and struggles to fit in with her peers, and Morgan Roberts is worried about how people will see her if she enters a high school math competition.

When Evelyn Valdez-Ward discovers that she's undocumented, she fears her dreams of becoming a scientist are over, and Samuel Achilefu's experiences growing up during the Nigerian Civil War inspire his passion for science. 

As a zoo volunteer, Lisa Yeager adores sharing her love of the wild, but one zoo patron is ruining that for her, and Anna yearns to be a scientist, but her strict mormon family doesn’t want her to become one.

When Saloni Singh’s mother is diagnosed with terminal cancer, Saloni is unexpectedly shoved into the role of caregiver and matriarch, and after her deaf mother has several strokes and begins experiencing hallucinations, Michelle Antonucci struggles to get her mom the care she needs.